Aortic Valve Replacement Without On-Site Surgery
Part of Heart & circulation clinical trials.
This study tests a catheter-based procedure to replace a narrowed aortic valve without traditional open-heart surgery. It's designed for patients who are at higher risk for surgery due to age, health conditions, or anatomy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic stenosis (a narrowed aortic valve) confirmed by your heart team
- Your heart team agrees you're a good candidate for TAVI (catheter-based valve replacement)
- You have at least one reason making surgery riskier (such as advanced age, frailty, lung disease, or heart problems)
- Your groin blood vessels are suitable for the catheter procedure
- You're able and willing to attend follow-up visits for at least 1 year
- You do not have another serious illness expected to limit your life to less than 1 year
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at placing a new aortic valve through the groin (transfemoral) without needing on-site heart surgery for people who are considered very high risk for standard open-heart valve surgery. It aims to measure early outcomes to see how safe and effective this approach is for frail or complex patients.
This trial tests a minimally invasive procedure called TAVI (transcatheter aortic valve implantation) to replace a narrowed aortic valve without requiring open-heart surgery. The study is checking whether TAVI can be safely performed at hospitals that don't have cardiac surgery units on-site.
This trial tests if a heart valve replacement procedure called TAVI can be safely done at heart centers that do not have a full heart surgery team available onsite. It is for people with severe narrowing of the aortic valve who are already planned for TAVI through the leg artery.
This trial tests if surgery to replace your aortic valve is safe and effective for people with severe aortic stenosis who are at low risk for complications. It compares surgery to another procedure to see which works best.
This study tests different access routes (non-groin pathways) for TAVI, a minimally invasive procedure to replace a narrowed aortic valve. If your groin vessels aren't suitable, this trial explores whether other body routes can safely deliver the new valve.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
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