Clin2
NCT07516704Possibly a fitNot yet recruiting

Combination drug treatment before prostate removal surgery

Prostate Cancer

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a combination of drugs given before prostate removal surgery. The goal is to see if this treatment can shrink or slow high-risk prostate cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
94 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are between 18 and 85 years old
  • You have been diagnosed with prostate cancer
  • Your cancer is considered high-risk (for example, it has spread, has a high Gleason score, or your PSA is above 20)
  • You are able to care for yourself (ECOG score 0-1)
  • You have not had any previous treatment for prostate cancer, such as radiation, chemotherapy, or hormone therapy
  • You have not had your prostate removed
  • You are willing to have your prostate removed as part of the study
  • You are not allergic to any of the study drugs

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07730151Not yet recruiting· Phase 2
Combination treatment before surgery for locally advanced prostate cancer

This trial tests a new combination of drugs given before surgery for locally advanced prostate cancer. The goal is to see if giving these drugs first helps shrink the tumor and improves outcomes after surgery.

NCT07677566Not yet recruiting· Phase 4
Combination treatment before surgery for high-risk prostate cancer

This trial tests a new combination of two drugs given before surgery to shrink high-risk prostate cancer. The goal is to see if this approach can improve outcomes for patients whose cancer is aggressive but has not spread.

Nanjing, Jiangsu
NCT07476677Not yet recruiting· Phase 2
Darolutamide with hormone therapy before surgery for high-risk prostate cancer

This study tests whether giving the drug darolutamide (with or without standard hormone therapy) before surgery helps shrink high-risk prostate cancer and reduce the chance of it coming back. If you qualify, you would receive the study treatment for a few months before your planned prostate removal surgery.

Beijing, Beijing Municipality
NCT06575257Recruiting· Phase 2
Darolutamide and Hormone Therapy Before Prostate Surgery

This trial tests giving a new hormone-blocking drug (darolutamide) plus standard hormone therapy before surgery for men with high-risk prostate cancer that has not spread. The goal is to see if this approach improves outcomes.

Xi’an, Shanxi
NCT07027124Recruiting· Phase 2
High-risk prostate cancer treatment before and after surgery

This trial tests a combination of hormone therapy, a targeted pill (Darolutamide), and an immunotherapy drug (Pembrolizumab) before and after surgery for men with high-risk prostate cancer that has specific genetic features. The goal is to see if this approach helps prevent the cancer from coming back.

New York, New York
NCT07282197Not yet recruiting· Phase 2
Darolutamide and hormone therapy after prostate surgery for high-risk prostate cancer

This trial tests a combination of two hormone therapies (darolutamide plus androgen deprivation therapy) given after surgery to remove the prostate, to see if it helps prevent the cancer from coming back in men with high-risk prostate cancer. The goal is to see if this treatment can keep the cancer from spreading or returning.

Beijing

Hear when a new Prostate cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.