Berberine effects on gut bacteria
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study tests whether berberine, a natural supplement, changes the bacteria in your gut. It may help prevent colon polyps from coming back after they've been removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have had a colonoscopy in the last 6 months.
- You either had one to six colon polyps removed, or you had no polyps found (healthy control).
- You are willing to provide stool and blood samples and answer questions about your health and lifestyle.
- You have not taken antibiotics, probiotics, or prebiotics in the last month.
- You are not regularly taking aspirin, NSAIDs (like ibuprofen), calcium, or vitamin D supplements.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study checks on people who took berberine in an earlier trial to see how they are doing 6 years later. It helps researchers understand the long-term effects of the treatment.
This study tests whether a natural compound called berberine (found in some plants) can improve heart and metabolic health in healthy adults. If you are healthy and meet the basic criteria, you may be able to join and contribute to research on preventing these conditions.
This trial tests whether taking a probiotic called Clostridium Butyricum after colon polyp removal can lower the chance of polyps coming back. It is looking for people who had adenomas removed and are not already taking certain supplements or antibiotics.
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
This study looks at how well a supplement called berberine is absorbed by the body when it is taken together with a special sugar compound (gamma-cyclodextrin). It is a phase 1 trial in healthy volunteers, meaning the focus is on safety and how the body handles the combination.
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