Clin2
NCT07527689Possibly a fitRecruiting

Faster vs. Standard Radiation After Breast Cancer Surgery

Breast Cancer

Part of Cancer, Skin clinical trials.

This study compares two radiation schedules for breast cancer patients at high risk of cancer returning in lymph nodes. Both use modern radiation therapy, but one delivers treatment faster (ultra-hypofractionated) while the other uses a more moderate schedule. The goal is to see which approach works better with fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,950 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with invasive breast cancer confirmed by biopsy
  • You've had breast surgery (lumpectomy or mastectomy) with lymph node staging
  • Your cancer is stage T1, T2, or T3 AND meets high-risk criteria (advanced lymph node involvement or early-stage nodes with other risk factors like age under 40, negative hormone receptor status, or grade 3 tumor)
  • Your surgical margins are clear (no cancer cells at the edge of removed tissue)
  • You are in good overall health (able to carry out most daily activities without major limitation)
  • You have not had previous radiation to your chest, underarm, or lower neck area

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03829553Recruiting· Phase 3
Radiation to breast lymph nodes versus standard breast cancer care

This Phase 3 trial tests whether a shorter, more focused radiation treatment to the regional lymph nodes works as well as the current standard approach for certain breast cancers. It may help patients by potentially improving treatment efficiency while keeping cancer control effective.

Shanghai, Shanghai Municipality
NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer

This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.

Shanghai, Shanghai Municipality
NCT07076485Recruiting· Phase 2
Shorter radiation after surgery for node-positive breast cancer

This trial tests shorter radiation schedules for people with breast cancer that has spread to lymph nodes or is high-risk. It aims to find a shorter course of radiation that is just as effective after surgery.

Loveland, Colorado
NCT06568705Recruiting· Phase 2
Shorter adaptive radiation for early breast cancer

This trial tests a shorter, more targeted course of daily radiation for early-stage breast cancer. The radiation plan is adjusted each day to better fit your body, which may reduce side effects.

Beijing
NCT05452083Not yet recruiting
Shorter radiation course after breast cancer surgery

This trial tests a shorter course of radiation therapy (called extreme hypofractionation) after surgery for early-stage breast cancer. It aims to see if fewer, higher-dose radiation sessions are as effective and safe as standard radiation, potentially reducing treatment time.

NCT05762900Recruiting· Phase 2
Shorter breast radiation after surgery for low-risk breast cancer

This Phase 2 trial tests a shorter, focused radiation treatment after breast surgery, either alone or with an extra targeted boost. It’s for people with low-risk breast cancer and no spread to distant organs, aiming to keep results while reducing treatment time and side effects.

Beijing

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.