Enzymes and healing after root canal treatment
Part of Mouth & dental clinical trials.
This study looks at whether certain natural enzymes (MMP-2 and MMP-3) in your mouth affect how well a root canal heals the infection at the tip of the root. If you have a single-rooted tooth with a confirmed infection, this trial may help determine if your healing could be predicted by these markers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The tooth must have only one root.
- The tooth must not have had a root canal before.
- You must have an infection at the root tip that is large enough to be seen on X-ray (score of 3 or more).
- Your gums must be fairly healthy (pockets around the tooth less than 5 mm deep).
- You must not have taken antibiotics in the last 4 weeks or painkillers in the last 48 hours.
- You cannot be pregnant, breastfeeding, or on immune-suppressing medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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