Sleep medication for adults with liver cirrhosis and insomnia
Treatments studied
Part of Brain & nervous system, Digestive system, Hormones & metabolism, Mental health clinical trials.
This trial tests a new sleep medication called daridorexant for people with liver cirrhosis who also have trouble sleeping. The study aims to see if the drug improves sleep quality and is safe for this group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- You must have a confirmed diagnosis of liver cirrhosis (with mild to moderate liver function, class A or B).
- You must have insomnia, proven by a sleep questionnaire and a sleep study or activity monitor.
- You cannot have severe liver failure (class C) or severe brain issues from liver disease.
- You cannot be taking certain other medications (like itraconazole, ketoconazole, carbamazepine, or rifampin), or central nervous system depressants (like alcohol, benzodiazepines, or opioids).
- You cannot have severe breathing problems, uncontrolled sleep apnea, narcolepsy, or be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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