Testing a new heart valve for moderate aortic stenosis
Part of Heart & circulation clinical trials.
This study compares a new artificial aortic valve (Myval THV) with standard medical treatment for people with moderate aortic stenosis—a condition where the heart valve doesn't open fully. The trial tests whether the new valve can help improve symptoms and heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years old or older
- You have moderate aortic stenosis confirmed by heart ultrasound or CT scan
- You have symptoms like shortness of breath, chest pain, or fainting OR you have no symptoms but show signs of heart damage on imaging
- Your heart's main pumping chamber (left ventricle) is not severely weakened (ejection fraction must be above 20%)
- You do not have severe kidney disease, severe leakage in other heart valves, or a life expectancy under 2 years from other serious illnesses
- You can safely have a heart procedure through blood vessels in your groin (transfemoral approach)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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