Early valve replacement for severe but symptom-free aortic narrowing
Part of Heart & circulation clinical trials.
This study looks at whether replacing a narrowed heart valve early helps people who have severe aortic stenosis but no symptoms. You would be randomly assigned to early valve replacement or careful waiting with regular check-ups.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 18
- You have severe aortic stenosis but no symptoms from it
- Your scan results match “severe” levels (including valve measurement and/or calcium score)
- Your heart pumping function is preserved (left ventricle ejection fraction 50% or higher)
- Your doctor believes you could safely have a valve procedure (surgery or TAVI) and you can consent
- You’re able to understand the study materials (or have a translator), and you can be randomized
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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