Comparing Two Sedation Drugs for ICU Patients on Breathing Support
Part of Lungs & breathing clinical trials.
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were admitted to an ICU between January 2022 and July 2024
- You received either ciprofol or propofol (sedation drugs) for at least 2 hours during your ICU stay
- Your sedation started while you were NOT on a breathing tube (invasive ventilation)
- You were receiving non-invasive breathing support (like oxygen mask, nasal tubes, or special high-flow oxygen) when sedation began
- Your medical records include sedation assessments and continuous monitoring of vital signs (heart rate, blood pressure, oxygen level, breathing rate)
- You did not receive other sedation drugs like midazolam or dexmedetomidine during the observation period
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two types of sedation (medicine to keep you calm and comfortable) for people in the intensive care unit (ICU) who need a breathing machine. It looks at which approach is more cost-effective and may help guide better care.
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
This study compares two different ways of giving the sedative medicine propofol during surgery that requires a breathing tube. The goal is to find which method is safer and works better for people having planned operations.
This trial compares two sedative medicines, ciprofol and propofol, to see which works better for older patients having surgery without a breathing tube. It aims to find the safer option for your heart and lungs.
This study compares two computer-controlled methods for delivering propofol sedation to ICU patients on a breathing machine. It aims to determine which method provides safer and more effective sedation for critically ill patients.
This study compares two medicines (propofol and ketamine) used to help you relax and stay stable while a breathing tube is placed. The goal is to see which one is safer for your heart and blood pressure during this procedure in the ICU.
Hear when a new Respiratory Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.