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NCT07537946Possibly a fitNot yet recruiting

Adding local treatment after immunotherapy for advanced liver cancer

Hepatocellular Carcinoma (HCC)Metastases

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests whether giving focused local treatment (like radiation or surgery) after a combination of two drugs, sintilimab and lenvatinib, can help control advanced liver cancer that has spread to a few other places. The goal is to see if this approach can shrink tumors and possibly extend life.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
400 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have advanced liver cancer (hepatocellular carcinoma) that has spread to 1 to 5 spots outside the liver, involving no more than 2 other organs.
  • You should not have received any previous treatment for advanced liver cancer, like immunotherapy or targeted pills.
  • You need to be in good general health (able to do light activities) and have adequate liver and kidney function.
  • You must not have major blood vessel invasion in the liver or a liver that is too full of tumors to treat locally.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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