Clin2
NCT06089382Possibly a fitNot yet recruiting

Adjuvant immunotherapy and targeted therapy for liver cancer with portal vein tumor thrombus

Hepatocellular Carcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests whether giving two medicines (an immunotherapy and a targeted therapy) after surgery can help prevent liver cancer from coming back in people with a specific type of tumor clot in the liver's main vein. If you've had surgery to remove the cancer and meet the health criteria, this treatment may lower your risk of recurrence.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
104 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have a type of liver cancer called hepatocellular carcinoma (HCC) that was confirmed by biopsy or after surgery.
  • You had surgery to remove the cancer and at least 4 weeks have passed since the surgery.
  • A tumor clot (thrombus) was found in the main vein of your liver (portal vein) during or after surgery.
  • You are between 18 and 75 years old, and you are in generally good health (able to do your daily activities).
  • You have not had any prior treatment for this liver cancer, like chemotherapy or radiation, before your surgery.
  • Your cancer has not spread beyond the liver, and you do not have serious other health conditions like autoimmune disease or poorly controlled high blood pressure.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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