Testing ALKS 2680 for narcolepsy type 1
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether a new medication called ALKS 2680 can help people with narcolepsy type 1 stay more awake and alert during the day. Narcolepsy type 1 is a neurological condition where people fall asleep unexpectedly and may experience sudden muscle weakness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with narcolepsy type 1, confirmed by a sleep study or CSF hypocretin test
- You do not have other sleep disorders or conditions affecting your sleep-wake cycle
- You are not currently in another clinical trial and have not taken any experimental medications in the past 30 days
- You do not have other serious medical conditions that could affect your safety in the study
- If you are a woman, you are not pregnant, breastfeeding, or planning to become pregnant during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medication, ALKS 2680, to see if it helps reduce daytime sleepiness and other symptoms in adults with narcolepsy type 1. It may offer a new treatment option for people with this condition.
This study is for people with narcolepsy or idiopathic hypersomnia who have already taken part in an earlier ALKS 2680 study. It aims to see how well the medication works and how safe it is when taken for a longer time.
This Phase 2/3 study tests TAK-861 in people with narcolepsy type 1 (NT1) who already completed an earlier TAK-861 trial. The goal is to see if the medicine remains safe and effective for ongoing central (brain-related) sleepiness problems.
This study tests a new medication called TAK-360 to help adults with narcolepsy type 1 (a condition that causes extreme daytime sleepiness and sudden muscle weakness called cataplexy) feel more alert during the day. The goal is to see if this treatment is safe and effective for managing narcolepsy symptoms.
This study tests whether a new medication called cleminorexton helps people with narcolepsy (a condition causing severe daytime sleepiness) sleep better and feel more alert. You would take this medication instead of your current narcolepsy drugs for several months to see if it works.
This trial tests a non-invasive brain stimulation method called temporal interference to target the hypothalamus. It aims to help reduce excessive daytime sleepiness in people with narcolepsy type 1.
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