Sitagliptin for recurrent grade 4 glioma
Treatments studied
Part of Cancer clinical trials.
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your grade 4 glioma has come back or progressed after initial treatment.
- You have not had sitagliptin or bevacizumab for this tumor before.
- You can swallow whole tablets and are in reasonably good health (ECOG 0-2).
- Your blood counts, kidney, and liver function are within safe limits.
- You do not have uncontrolled diabetes, heart problems, or a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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