Sitagliptin for people with high-grade brain tumors
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a grade 4 glioma (a fast-growing brain tumor) and are scheduled for surgery to remove it.
- You have not taken sitagliptin or similar drugs before.
- You are at least 18 years old and able to swallow whole tablets.
- Your kidney, liver, and blood cell counts are within safe limits.
- You can take a low dose of steroid medicine (dexamethasone) before surgery if needed.
- You have not had a different cancer that could interfere with this study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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