Treatment
Sitagliptin clinical trials
We’re tracking 15 recruiting studies that include Sitagliptin, each written for real people, not researchers, below.
Recruiting studies
- NCT06587698Recruiting
Study of sitagliptin or BeiDouGen capsule for PCOS pregnancy
This trial tests if sitagliptin or BeiDouGen capsule can improve pregnancy outcomes in women with PCOS. It aims to help those planning to conceive or struggling with infertility.
Beijing, Beijing MunicipalityAges 20–40 - NCT05947825Enrolling by invitationPhase 2
Sitagliptin plus chemo for advanced pancreatic cancer
This trial tests adding sitagliptin (a diabetes drug) to standard chemotherapy (gemcitabine and nab-paclitaxel) for people with pancreatic cancer that has spread or cannot be removed by surgery. The goal is to see if the combination works better than chemo alone.
TianjingAges 18 years+ - NCT07634380RecruitingPhase 1
Sitagliptin Plus Pembrolizumab for Advanced Kidney or Skin Cancer
This study tests whether adding sitagliptin (a diabetes medication) to pembrolizumab (an immunotherapy) can help patients with advanced kidney cancer or melanoma whose cancer stopped responding to previous immunotherapy treatments. The goal is to see if this combination can shrink tumors and improve survival.
Iowa City, IowaAges 18–99 - NCT07003542RecruitingPhase 2
Sitagliptin for people with high-grade brain tumors
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
Cleveland, OhioAges 18 years+ - NCT07365592RecruitingPhase 1/Phase 2
Neoadjuvant therapy for locally advanced colorectal cancer
This trial tests a combination of chemotherapy, an immunotherapy drug (anti-PD-1 antibody), and sitagliptin before surgery for colorectal cancer that has not spread to other organs. The goal is to see if this approach can shrink the tumor and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07541781RecruitingPhase 1
Sitagliptin for recurrent grade 4 glioma
This trial tests whether the diabetes drug sitagliptin (Januvia) can help slow or shrink a recurrent grade 4 glioma (a type of brain tumor). It's for people whose tumor has come back after standard treatment and who have not used sitagliptin or Avastin before.
Iowa City, IowaAges 18 years+ - NCT07452913Enrolling by invitationPhase 4
Comparing Diabetes Drug Combinations in Newly Treated Adults
This trial compares two different combinations of diabetes pills (metformin plus empagliflozin with either sitagliptin or linagliptin) in people with type 2 diabetes who have not been treated before. It aims to see which combination works better and is safer for controlling blood sugar.
Karachi, SindhAges 30–55 - NCT07073768Enrolling by invitationPhase 3
Comparing two diabetes pills for type 2 diabetes
This study compares two medications, trelagliptin and sitagliptin, to see which works better for people with type 2 diabetes. It might be an option if you are already taking metformin but your blood sugar levels are still not under control.
Peshawar, Khyber PakhtunkhwaAges Any age - NCT05195944Enrolling by invitationPhase 4
Semaglutide versus sitagliptin after liver transplant for diabetes
This trial compares two diabetes medicines—semaglutide and sitagliptin—in people who have had a liver transplant and have type 2 diabetes (or diabetes after transplant). It’s looking to see which medicine works better and is safe for blood sugar control in the transplant setting.
Toronto, OntarioAges 18 years+ - NCT07717242RecruitingPhase 2
Bladder cancer study testing a new drug combination before surgery
This trial is testing a combination of two drugs (disitamab vedotin and toripalimab) for people with muscle-invasive bladder cancer that has not spread. The goal is to see if this treatment can shrink the tumor before surgery. You may qualify if your tumor has a certain level of a protein called HER2.
Guangzhou, GuangdongAges 18 years+ - NCT07711171RecruitingPhase 4
Canagliflozin for type 2 diabetes with mild memory problems
This trial tests whether the diabetes drug canagliflozin can help people with type 2 diabetes and mild cognitive impairment. It may slow down memory and thinking problems while also improving blood sugar control.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT06246799RecruitingPhase 3
Comparing two pill combinations for new diabetes
This study compares two different two-drug combinations for people recently diagnosed with type 2 diabetes. It aims to find which combination works better to control blood sugar and improve overall health.
San Antonio, TexasAges 18–75 - NCT06329882RecruitingPhase 1/Phase 2
Doxycycline for newly diagnosed type 2 diabetes
This trial tests whether the antibiotic doxycycline can help control blood sugar in people newly diagnosed with type 2 diabetes. If you are over 40 and have not taken diabetes medications yet, you may be able to join.
TantaAges 40–60 - NCT06515652Recruiting
Herbal vs standard medicines for metabolic syndrome
This study compares herbal medicines to standard medications for people with metabolic syndrome—a group of conditions like high blood pressure, high blood sugar, and excess belly fat. The goal is to see if herbs work as well as traditional drugs, with fewer side effects.
Karachi, SindhAges 35–65 - NCT07374328RecruitingPhase 1/Phase 2
Three diabetes medicines for new type 2 diabetes
This trial tests a combination of three diabetes medicines to see if they can quickly get high blood sugar under control in people newly diagnosed with type 2 diabetes. It's designed for those whose HbA1c is 9.0% or higher.
Guangzhou, GuangdongAges 18–65
What Sitagliptin is being studied for
Conditions with recruiting Sitagliptin studies.
Common questions
- Are there clinical trials studying Sitagliptin?
- Yes. Clin2 currently lists 15 recruiting studies that include Sitagliptin, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Sitagliptin trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Sitagliptin an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Sitagliptin or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.