Low-dose immunotherapy for advanced colorectal and stomach cancer
Part of Cancer, Digestive system clinical trials.
This study tests a lower dose of immunotherapy in patients with colorectal or stomach cancer that has spread or cannot be removed by surgery. The cancer must have a specific genetic feature (MSI/dMMR). The goal is to see if this approach works well with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colorectal (colon or rectum) or stomach cancer confirmed by biopsy
- Your cancer has MSI or dMMR (a genetic marker that makes immunotherapy more effective)
- You are either 18+ years old and able to give informed consent
- Your cancer cannot be easily removed surgically, or has spread to other parts of your body
- You have not had certain immunotherapy drugs (anti-PD-1, anti-PD-L1, or anti-CTLA4) before
- You are generally healthy enough for treatment (ECOG score 0–2)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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