Real-world study of inavolisib for advanced breast cancer
Part of Cancer, Skin clinical trials.
This study observes how inavolisib (a new cancer drug) works in patients with a specific type of advanced breast cancer in everyday clinical practice. Researchers will track your medical records, imaging, and lab results over time to understand how well the treatment works and its safety profile.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with HR-positive/HER2-negative breast cancer that has spread (recurrent or metastatic)
- Your cancer has a PIK3CA genetic mutation confirmed by a blood or tissue test
- You have already started treatment with inavolisib combined with hormone therapy, with or without a CDK4/6 inhibitor
- Your medical records, imaging scans, and lab results are available and traceable at the start of the study
- You are willing to provide written consent and allow researchers to access your ongoing medical information
- You are not currently enrolled in another clinical trial testing a new drug
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new targeted therapy, inavolisib, combined with standard hormone therapy and a CDK4/6 inhibitor for people with a specific genetic mutation (PIK3CA) in their hormone receptor-positive, HER2-negative advanced breast cancer that has not been treated before. It compares this combination to a placebo plus the same standard treatments.
This trial tests whether a new targeted pill (inavolisib) plus hormone therapy (fulvestrant) can slow or stop breast cancer growth in people whose cancer has a specific genetic change called a PIK3CA mutation. It is for patients whose disease worsened after previous hormone-and-CDK-inhibitor treatment.
This trial is testing a drug called Inavolisib (a type of targeted therapy) given before surgery for people with early-stage, hormone receptor-positive, HER2-negative breast cancer that has a specific genetic change (PIK3CA mutation). The goal is to see if adding Inavolisib to standard endocrine therapy can shrink the tumor more effectively.
This trial tests a new drug, inavolisib, combined with two standard treatments (fulvestrant and palbociclib) for people with advanced breast cancer and type 2 diabetes. It aims to find out if this combination is safe and effective.
This study tests a combination of three drugs (inavolisib, ribociclib, and fulvestrant) for women with advanced breast cancer that is hormone-receptor positive and HER2-negative, with a specific genetic mutation (PIK3CA). The goal is to see if this combination can shrink or control the cancer better than standard treatments.
This trial tests a combination of three drugs (inavolisib, ribociclib, and fulvestrant) compared to a placebo plus two of the drugs (ribociclib and fulvestrant) for people with advanced hormone receptor-positive breast cancer who have not had prior treatment for advanced disease. The goal is to see if adding inavolisib improves outcomes.
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