Knee Arthritis Injection: Two Injection Methods Compared
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 50 or older
- You have been evaluated at one of the 4 study clinics by one of the participating doctors
- You have had recent imaging (X-rays and/or MRI) showing osteoarthritis in at least one knee
- You have symptoms from knee osteoarthritis, such as pain or stiffness
- You have not had any joint injections (steroid, hyaluronic acid, or PRP) in the past 3 months
- You can understand and communicate in English or Spanish
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new knee injection called CX-011 to see if it can reduce pain and improve function in people with knee osteoarthritis. It may be a good option if you have tried other treatments without enough relief.
This study tests if steroid injections for knee arthritis work in people with obesity. It may help you manage pain and avoid surgery.
This study compares two different steroid knee injections—Zilretta and Kenalog—to see which works better for people with both knee osteoarthritis and type 2 diabetes. It uses a continuous glucose monitor to track blood sugar changes.
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
This study tests if an injection made from amniotic fluid can reduce knee pain and improve function in people with moderate knee osteoarthritis. The goal is to give a long-lasting alternative to steroid or gel shots.
Hear when a new Knee Arthritis Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.