Clin2
NCT07555431Possibly a fitRecruiting

Dolutegravir alone versus with tenofovir for HTLV-1

HTLV-1 InfectionHTLV I Associated MyelopathiesHTLV I Associated T Cell Leukemia LymphomaNeuritis

Treatments studied

Part of Blood & lymphatic, Brain & nervous system, Cancer, Immune system & allergy, Infections clinical trials.

This study tests whether adding tenofovir (an antiviral medication) to dolutegravir helps treat HTLV-1 infection better than dolutegravir alone. HTLV-1 is a virus that can cause serious health problems, and researchers want to find the most effective treatment combination.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
146 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older
  • You have confirmed HTLV-1 infection (a blood test showing the virus)
  • You have symptoms or health problems caused by HTLV-1
  • You do not have HIV, hepatitis C, or hepatitis B infections
  • You do not have active tuberculosis
  • Your kidneys function well enough (not severely damaged)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06203132Recruiting· Phase 3
Doravirine vs Dolutegravir for first-time HIV treatment

This study compares two HIV medicines, doravirine and dolutegravir, to see which works better for people who have never taken HIV treatment before. If you qualify, you would be randomly assigned to one of the two medications.

Nova Iguaçu, Rio de Janeiro
NCT06497465Recruiting· Phase 3
Two-drug HIV treatment for people with TB

This trial tests a two-drug HIV treatment for people who are new to HIV therapy and also have tuberculosis. It compares the two-drug combination to the standard three-drug regimen, with the goal of making treatment simpler while still being effective.

Manaus, Amazonas
NCT06762054Recruiting
Better management for dolutegravir-resistant HIV

This trial tests better ways to manage HIV when the virus becomes resistant to dolutegravir (DTG), a key medicine. It is for people with high viral load despite being on DTG for at least six months.

Kisumu
NCT06637813Not yet recruiting
Dual therapy with dolutegravir and lamivudine for HIV

This study collects information from people with HIV who are either starting HIV treatment for the first time or switching from a three-drug regimen to a two-drug regimen with dolutegravir and lamivudine. The goal is to build a database to learn how well this dual therapy works in real-world practice.

NCT03884673Recruiting
Simpler two-drug HIV treatment with dolutegravir and lamivudine

This trial studies whether taking dolutegravir plus lamivudine (a simpler two-drug regimen) can work as well as a standard three-drug HIV regimen for people who have reasons they can’t stay on the usual medicines. You may be offered free treatment if you meet the safety checks and can attend follow-up visits.

Guangzhou, Guangdong
NCT07616739Recruiting· Phase 4
Dolutegravir and Lamivudine for Pregnant Women with HIV

This study tests a two-drug HIV treatment combination (dolutegravir and lamivudine) for pregnant women who have never taken HIV medicine before. The goal is to see if this combination safely controls HIV during pregnancy and protects the baby.

Ciudad Autónoma de Buenos Aires, Buenos Aires

Hear when a new HTLV-1 Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.