Clin2
NCT07559890Possibly a fitRecruiting

Nerve ablation for low back pain with Modic changes

Chronic Back PainBasivertebral Nerve Ablation

Part of Bones, joints & muscles, Pain clinical trials.

This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have had low back pain for at least 6 months that stays in the center (not shooting down your leg).
  • An MRI shows Modic type I or II changes (a type of bone marrow inflammation) in at least one vertebra.
  • You have tried at least 3 months of non-surgical treatments (like physical therapy, medications, or injections) without enough relief.
  • You have not had any previous spine surgery.
  • You do not have osteoporosis, bleeding disorders, or cancer that has spread.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain

This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.

Guilford, Connecticut
NCT07392333Recruiting
Nerve ablation for chronic low back pain

This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.

Fort Lauderdale, Florida
NCT07696507Not yet recruiting
Nerve ablation for chronic low back pain from spine changes

This trial tests a procedure that uses heat to treat specific nerves in the spine that may be causing chronic low back pain. It's for people who haven't gotten better with other treatments and have a certain type of bone marrow change seen on MRI.

Cagliari
NCT04730700Recruiting
Radiofrequency treatment test for facet back pain

This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.

Kansas City, Kansas
NCT05641948Recruiting
Tested nerve ablation plus brain scans for ongoing back pain

This trial studies a procedure called radiofrequency denervation to reduce long-lasting, mostly “pain-from-joints/structures” low back pain, and it uses brain imaging to understand what changes during treatment. It may help people who already showed they respond well to a similar diagnostic nerve block.

Aberdeen, Scotland
NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain

This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.

The Bronx, New York

Hear when a new Chronic Back Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.