Long-term outcomes after fetal lung surgery for diaphragmatic hernia
Part of Genetic & congenital clinical trials.
This study follows babies born after a special fetal surgery (FETO) that places a temporary balloon in the baby's windpipe to help the lungs grow when they have a diaphragmatic hernia—a hole in the muscle that separates the chest from the belly. Researchers want to understand how these children do over time after this procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are carrying one baby (not twins or multiples)
- The baby's chromosomes are normal, confirmed by genetic testing
- You are less than 29 weeks 6 days pregnant at the time you enroll
- Your baby has a diaphragmatic hernia with specific severity measurements on ultrasound (left side: less than 30% or right side: less than 45% organ displacement)
- Your cervix is longer than 20 mm checked within 2 days before the surgery
- You can live within 30 minutes of Mayo Clinic and have a support person to stay with you during pregnancy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether placing a small balloon in the fetus’s airway during pregnancy (a procedure called FETO) can improve lung development and outcomes for babies with severe left congenital diaphragmatic hernia. You may be considered if the condition is isolated, very severe, and you can meet specific timing and follow-up requirements.
This trial tests a procedure called fetoscopic tracheal occlusion to improve lung growth in babies with a severe diaphragmatic hernia. It is for pregnant women carrying a single baby with certain types of this condition, and the goal is to see if the procedure is safe and effective.
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
This study follows pregnant women and their babies after a special fetal surgery (FETO) for severe diaphragmatic hernia (CDH). It aims to understand long-term health outcomes for both mother and child.
This study tests a fetal surgery (fetoscopic tracheal balloon placement) to help lungs grow in babies with a severe hole in the diaphragm. It focuses on pregnancies where the liver is also in the chest and lung size is very small.
This trial studies a fetal procedure called FETO (placing a small balloon in the baby’s windpipe) to help severe congenital diaphragmatic hernia babies develop better lungs before birth. It may help some babies whose scans suggest very limited lung growth, but it requires specific timing and pregnancy conditions.
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