Long-term outcomes after fetal surgery for severe CDH
Part of Genetic & congenital clinical trials.
This study follows pregnant women and their babies after a special fetal surgery (FETO) for severe diaphragmatic hernia (CDH). It aims to understand long-term health outcomes for both mother and child.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and pregnant with one baby.
- Your baby has a severe form of left or right CDH (a hole in the diaphragm).
- You are less than 30 weeks pregnant when you start the study.
- You do not have certain infections (HIV, hepatitis B or C) or other serious health conditions.
- You are able to stay within 30 minutes of Johns Hopkins Hospital for the rest of your pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if placing a temporary balloon in the baby's windpipe before birth can improve survival for babies with a severe form of a diaphragmatic hernia. It is for pregnant women carrying a single baby with a left-sided hernia that is more severe or a right-sided hernia, and whose liver is up in the chest.
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
This study follows babies born after a special fetal surgery (FETO) that places a temporary balloon in the baby's windpipe to help the lungs grow when they have a diaphragmatic hernia—a hole in the muscle that separates the chest from the belly. Researchers want to understand how these children do over time after this procedure.
This trial tests a procedure called FETO (fetoscopic endoluminal tracheal occlusion) performed during pregnancy to help babies with congenital diaphragmatic hernia—a birth defect where part of the diaphragm (breathing muscle) has a hole and organs from the belly move into the chest. The procedure temporarily blocks the baby's windpipe to help the lungs grow bigger before birth.
This trial studies a fetal procedure called FETO (placing a small balloon in the baby’s windpipe) to help severe congenital diaphragmatic hernia babies develop better lungs before birth. It may help some babies whose scans suggest very limited lung growth, but it requires specific timing and pregnancy conditions.
This study tests a fetal surgery (fetoscopic tracheal balloon placement) to help lungs grow in babies with a severe hole in the diaphragm. It focuses on pregnancies where the liver is also in the chest and lung size is very small.
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