Psilocybin with a serotonin blocker in healthy adults
Treatments studied
This early-stage research study tests how psilocybin (a naturally occurring compound from certain mushrooms) works when combined with a medication that blocks a specific serotonin pathway in the brain. Researchers want to understand how these two substances interact in healthy volunteers to inform future psychiatric treatment studies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 21 and 60 years old
- Be in good overall health with no serious heart, brain, or psychiatric conditions
- Pass medical screening including blood tests, urine tests, and an ECG (heart recording)
- Agree to stop all recreational drugs and most medications for 24 hours before each study session
- Commit to using reliable birth control if you can become pregnant, or agree to contraception if male
- Have a high school diploma or equivalent and be fluent in English
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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