Clin2
NCT07565623Possibly a fitNot yet recruiting

Steroid to prevent immune overreaction in HIV starting treatment

HIV (Human Immunodeficiency Virus)IRIS

Treatments studied

Part of Immune system & allergy, Infections clinical trials.

This trial tests whether giving a steroid can prevent severe immune overreactions in people starting HIV treatment who have had an AIDS-related infection. It aims to reduce complications and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
131 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have HIV.
  • You must have an AIDS-related infection (like PJP pneumonia, cryptococcal meningitis, or CMV retinitis).
  • Your CD4 count (immune cell count) must be below 100.
  • You need to be starting HIV treatment soon.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07851337Not yet recruiting· Phase 2
Glatiramer acetate for immune recovery in people with HIV

This trial tests a medicine called glatiramer acetate (often used for multiple sclerosis) to see if it can help improve the immune system (CD4 cells) in people with HIV who have low CD4 counts despite successful viral suppression. It involves injecting the medicine under the skin three times a week for the study period.

NCT07332325Not yet recruiting· Phase 3
Steroids and enhanced antibiotics for sepsis in people with HIV

This study tests whether a combination of steroids (a type of medicine that reduces inflammation) and stronger antibiotics can help people with HIV who have a serious infection (sepsis) that is not getting better with standard treatment. If you qualify, you may receive this extra treatment to see if it helps you recover.

Mwanza
NCT03856229Enrolling by invitation
Short steroid treatment for lung infection from PCP in HIV

This study tests whether short-term steroid treatment helps adults with a specific lung infection (PCP) that happens with HIV/AIDS. It compares outcomes in people who start steroids soon after admission while also taking standard PCP antibiotics.

México, State of Mexico
NCT07081763Not yet recruiting· Phase 2
Testing baricitinib and sirolimus to control HIV after stopping treatment

This study tests two drugs, baricitinib and sirolimus, alone or together, to see if they can help control HIV after you stop your usual HIV medications for a short time. The goal is to see if these drugs can keep the virus from rebounding.

NCT07875504Not yet recruiting
A pause in HIV treatment for people with a strong immune profile

This trial tests whether you can safely stop your HIV medication for a while if your immune system has specific markers that might help control the virus. The goal is to see if a treatment pause could be an option for people like you.

NCT07145164Enrolling by invitation· Phase 2
IL-15 to boost HIV control after pausing daily meds

This study tests whether giving a small protein called IL-15 can help your immune system keep HIV under control after pausing your daily HIV medications. You will stop your meds for a short time under careful monitoring, and the hope is that your body might learn to fight HIV without daily pills.

San Francisco, California

Hear when a new HIV (Human Immunodeficiency Virus) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.