Mirabegron to Control Dangerous Heart Rhythms
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether mirabegron, a medication originally used for bladder control, can help reduce dangerous heart rhythms (VT) in people who already have an implanted defibrillator (ICD). Researchers believe it may work by calming nerve activity that triggers these dangerous rhythms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have an implanted defibrillator (ICD) and have experienced more than 2 dangerous heart rhythms (VT) per month over the past 2 months, even while on standard heart medications
- You are not dependent on your pacemaker for your heartbeat
- Your blood pressure, kidney function, liver function, and thyroid are stable and within safe ranges
- You are not pregnant or breastfeeding and can communicate in English
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This trial tests a new catheter-based procedure to treat life-threatening irregular heartbeats (ventricular tachycardia) that keep coming back despite medication. If you've had a heart attack and your implanted defibrillator hasn't fully controlled these arrhythmias, this procedure might help prevent future episodes.
This study compares two catheter-based procedures to treat ventricular tachycardia (VT), a fast, dangerous heart rhythm. It looks to see which approach works better at reducing repeat VT events in people with weakened heart pumping.
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