Vaccine therapy for advanced solid tumors
Treatments studied
Part of Cancer clinical trials.
This study tests a new therapeutic vaccine designed to help your immune system fight advanced solid cancers. You would receive vaccine injections alongside standard cancer care if your cancer has progressed despite previous treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed advanced solid tumor (bone, pancreas, head/neck, colon, liver, brain, or breast cancer) that has progressed or returned after prior chemotherapy or other treatments
- You are between 18 and 75 years old with good enough overall health to tolerate the vaccine (ECOG score 0–2)
- You have a life expectancy of more than 3 months
- Your blood counts, liver, and kidney function are adequate (checked within 7 days before treatment starts)
- You do not have active brain metastases, serious infections (HIV, hepatitis B or C, tuberculosis), or uncontrolled autoimmune disease
- You are not pregnant or breastfeeding, and willing to use contraception during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new vaccine (YMN-136) for people with colorectal cancer that has spread to the liver and hasn't responded to at least three prior treatments. The goal is to see if the vaccine can help control the cancer.
This trial tests a new vaccine made from your own tumor cells to see if it can help your immune system fight the cancer. It is for people with advanced solid tumors that have not responded to other treatments.
This trial is testing an investigational vaccine (YMN-136) for people with advanced liver, bile duct, or pancreatic cancer that has not responded to standard treatments or is not tolerated. The vaccine aims to help your immune system fight the cancer. It may be an option if standard treatments have failed.
This early-phase trial tests a new type of cancer vaccine designed to help your immune system attack tumors. It is for people with advanced solid tumors who have run out of standard options.
This early-stage trial tests a new mRNA-based drug designed to help your immune system fight advanced cancers that haven't responded to standard treatments. The study measures safety, tolerability, and whether it can slow or shrink your tumor.
This trial tests a personalized vaccine made from “neoantigens” (tumor-specific targets) to help your immune system fight advanced, inoperable solid tumors. It may be an option if standard treatment didn’t work or you stopped it and your health is strong enough for trial treatment.
Hear when a new Malignant Neoplasm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.