Testing efgartigimod for Graves' disease hyperthyroidism
Treatments studied
Part of Eyes & vision, Hormones & metabolism, Immune system & allergy clinical trials.
This study tests whether efgartigimod, an injectable medication given under the skin, can help control overactive thyroid (Graves' disease) in adults already taking methimazole or carbimazole. The goal is to see if it reduces thyroid antibodies and improves thyroid hormone levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have been diagnosed with Graves' disease and have elevated thyroid antibodies (TRAb) at screening
- You have active hyperthyroidism (low TSH below 0.1) caused by Graves' disease
- You have been taking methimazole or carbimazole for at least 3 months before screening
- You have not had radioactive iodine treatment or thyroid surgery in the past
- You do not have uncontrolled heart rhythm problems related to your overactive thyroid (like uncontrolled atrial fibrillation)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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