Modafinil for Fatigue in Controlled Inflammatory Bowel Disease
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether modafinil (a wakefulness-promoting medication) can reduce severe fatigue in people with inflammatory bowel disease (IBD) whose disease is well-controlled. If you have persistent exhaustion despite your IBD being stable, this study may help determine if this medication works for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–75 with at least 1 year of confirmed IBD diagnosis (Crohn's disease, ulcerative colitis, or IBD-unclassified)
- Severe fatigue lasting 6+ months, confirmed by a specific fatigue score
- IBD is currently quiet or in remission (no active inflammation on recent testing)
- Stable IBD medications for 3+ months with no planned changes during the trial
- No contraindications to modafinil, including uncontrolled high blood pressure, heart rhythm problems, or certain other conditions
- Able to complete Dutch-language online questionnaires and attend all study visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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