Testing Two Obesity Drugs Together in Adults
Part of Hormones & metabolism clinical trials.
This study tests whether combining two new medications (petrelintide and enicepatide) can help adults with obesity or overweight lose weight. Both drugs work on your body's appetite and metabolism control systems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- BMI of 30 or higher, OR BMI between 27–30 with a weight-related health condition (like high blood pressure or joint problems)
- You have tried dieting on your own but were unable to lose weight
- No type 1 or type 2 diabetes, and a blood sugar test (HbA1c) below 6.5%
- No recent weight surgery, endoscopic procedures, or weight-loss devices (excluding certain cosmetic procedures done over 1 year ago)
- Haven't taken GLP-1 weight-loss drugs (like semaglutide, tirzepatide) in the last 6 months
- No history of pancreatitis, severe psychiatric illness, or NYHA Class IV heart failure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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