Clin2
NCT07594236Likely a fitRecruiting

Experimental Cell Therapy for Retinal Degeneration

Geographic AtrophyStargardt DiseaseRPE-mediated MaculopathyAge Related Macular Degeneration

Part of Eyes & vision, Genetic & congenital clinical trials.

This early-stage study tests a new cell-based treatment (C.001) for inherited retinal diseases that affect the back of the eye. The treatment may help slow vision loss or improve sight in people with geographic atrophy or Stargardt disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
15 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Age 18 or older
  • Diagnosed with geographic atrophy, Stargardt disease, or similar retinal pigment epithelium degeneration
  • Vision within acceptable range for the study
  • Eye condition stable before starting the trial
  • Healthy enough for eye surgery and anesthesia
  • Willing to attend follow-up visits and comply with study instructions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06557460Recruiting· Phase 2
Cell implant for advanced dry age-related macular degeneration

This trial tests a patch of retinal cells implanted under the retina to see if it can slow or stop vision loss from advanced dry AMD (geographic atrophy). It may help people whose central vision is already affected.

Beverly Hills, California
NCT07439887Recruiting· Phase 1/Phase 2
Study of an injection for Stargardt disease

This trial tests a single injection of a new medicine, RTx-021, into the eye for people with Stargardt disease. The goal is to see if it is safe and to find the right dose.

Bakersfield, California
NCT05626114Recruiting· Phase 2
Study of a lab-made eye treatment after subretinal surgery

This Phase 2 study tests OpRegen, a treatment delivered during special eye surgery, for geographic atrophy related to age-related macular degeneration (GA from AMD). It also includes an imaging “substudy” that uses detailed pictures of your retina to better track safety and activity.

Beverly Hills, California
NCT06394232Recruiting· Phase 1/Phase 2
Testing a cell therapy for advanced dry AMD with geographic atrophy

This trial tests a new treatment called Eyecyte-RPE™, made from special cells that support the retina. It is given as a single injection under the retina during eye surgery. The study aims to see if it can help people with advanced dry age-related macular degeneration (AMD) who have large areas of damage (geographic atrophy) in the center of their vision.

Jālna, Maharashtra
NCT05991986Not yet recruiting
Retinal cell therapy for advanced age-related macular degeneration

This trial tests if using your own stem cells to create retinal cells can help treat advanced age-related macular degeneration (AMD). If you have severe vision loss from AMD, this approach may restore some sight.

NCT04339764Recruiting· Phase 1/Phase 2
iPS cell eye transplant for dry macular degeneration

This early-phase study tests whether transplanting lab-made retinal cells from your own body can slow vision loss from geographic atrophy caused by dry age-related macular degeneration. It involves eye surgery and frequent follow-up to check safety and early signs of benefit.

Baltimore, Maryland

Hear when a new Geographic Atrophy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.