Ketamine and therapy for treatment-resistant depression
Treatments studied
Part of Mental health clinical trials.
This study combines behavioral activation therapy (a type of counseling that helps you re-engage in positive activities) with ketamine infusions to treat depression that hasn't improved with standard antidepressants. The goal is to see if adding this therapy makes ketamine work better and last longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depressive disorder (clinical depression) and are currently in a moderate or severe episode without hallucinations or delusions.
- At least two different antidepressants have not helped enough in this current episode.
- You are under a doctor's care and willing to keep your current medications stable during the study.
- You can arrange for someone to drive you home after each ketamine infusion.
- You are not pregnant or breastfeeding, and if you could become pregnant, you agree to use reliable birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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