Clin2
NCT07604909Possibly a fitRecruiting

Serplulimab plus chemotherapy for early-relapsed colorectal cancer

Colorectal CancerRelapse

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new immunotherapy drug called serplulimab combined with standard chemotherapy or targeted therapy for colorectal cancer that has come back within a year after surgery. The goal is to see if adding this immune-boosting drug helps control the cancer better than chemotherapy alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You were diagnosed with colorectal cancer that came back within 1 year after surgery (stage IV with cancer spread)
  • You completed standard post-surgery chemotherapy (XELOX or FOLFOX regimen)
  • Your tumor tissue has been tested and shows pMMR, MSS, or MSI-L status (not MSI-H)
  • You have at least one measurable tumor spot on imaging scans
  • Your overall health is good enough for treatment (ECOG performance 0–1)
  • Your blood counts, liver, kidney, and thyroid function are adequate

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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