Clin2
NCT07605806Possibly a fitRecruiting

Understanding Drug Reactions to Vancomycin

Healthy VolunteerHypersensitivity ReactionsVancomycin

Treatments studied

Part of Immune system & allergy clinical trials.

This research study tests a new antibiotic called vancomycin to understand how the body reacts to it and identify early warning signs. If you qualify, you'll help researchers learn more about sudden allergic-like reactions that aren't traditional allergies.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
25 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Age 18 or older
  • Healthy kidney function (normal creatinine level)
  • Never received vancomycin before in any form
  • No history of allergic reactions to vancomycin or similar antibiotics
  • Able to speak and read English at an 8th grade level for safety communication
  • Willing to use effective birth control if you can become pregnant

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05964114Not yet recruiting
Test whether first-time vancomycin dosing works right

This study looks at giving vancomycin continuously in the ICU or orthopedics for the first time, to see if the dosing is done correctly. If you’re an adult receiving this treatment, the trial may help improve how safely and accurately vancomycin is managed.

NCT07084129Recruiting· Phase 1
Vancomycin and kidney injury study for children with sepsis

This trial tests a different way of giving vancomycin to children with sepsis to reduce the risk of kidney injury. It compares standard dosing to an approach that adjusts dose based on how the kidneys are working.

Philadelphia, Pennsylvania
NCT06954129Recruiting· Phase 4
Comparing two antibiotic combos for infection and kidney safety

This trial compares two common antibiotic combinations to see which one is less likely to cause kidney injury in hospitalized patients. You may be eligible if you need treatment with vancomycin plus either piperacillin-tazobactam or cefepime.

Philadelphia, Pennsylvania
NCT05084196Recruiting· Phase 3
Melatonin to help prevent kidney damage from vancomycin

This Phase 3 study tests whether melatonin can help protect the kidneys in people who are starting or continuing vancomycin, an antibiotic that can sometimes affect kidney function. If you qualify, you would take melatonin as an added prevention step while you’re on vancomycin.

New Brunswick, New Jersey
NCT04793152Recruiting
Tested vancomycin dosing for serious MRSA using different lab targets

This trial compares two ways of dosing vancomycin (an antibiotic) for serious MRSA infections by using different blood test targets. The goal is to see if the newer approach works at least as well as the standard one, while keeping patients safe.

Hamilton, Ontario
NCT05539729Recruiting· Phase 1
Testing vancomycin for newly diagnosed multiple sclerosis

This Phase 1 study tests whether the antibiotic vancomycin can be given safely to people with newly diagnosed multiple sclerosis (or related early stages). It mainly focuses on safety and side effects, and whether the approach is feasible for this group.

New York, New York

Hear when a new Hypersensitivity Reactions trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.