Immune Reset to Help Highly Sensitized Kidney Transplant Patients
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether a special immune-resetting treatment can help patients who have developed too many antibodies against donor kidneys get access to a compatible kidney transplant. The treatment uses chemotherapy and stem cell transplantation to 'reset' your immune system so it stops rejecting potential donor kidneys.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–60 years old
- You have end-stage kidney disease and are currently on dialysis
- You are highly sensitized (have very high levels of antibodies against donor kidneys, typically ≥95%)
- You are currently on a deceased-donor kidney transplant waiting list
- Your heart, lungs, liver, and bone marrow are healthy enough to safely handle strong chemotherapy and stem cell transplantation
- You can understand the study and commit to long-term follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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