JAK inhibitor for depression in male football players
Treatments studied
Part of Brain & nervous system clinical trials.
This study tests a new medication (a JAK inhibitor) that may reduce brain inflammation and improve depression and thinking in male football players. It aims to see if this treatment helps with mood and cognitive function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be male
- You must have played tackle football for at least 11 years
- You must be between 30 and 55 years old
- You must have a current or partially remitted diagnosis of major depression or bipolar depression
- You must have moderate to severe depressive symptoms (e.g., a score above 10 on a depression scale)
- You must not have certain medical conditions (autoimmune disorders, infections, cancer, unstable organ disease, blood clots, stroke, recent major surgery, or cirrhosis)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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