Clin2
NCT07612891Possibly a fitRecruiting

Testing INV-6452 for advanced breast cancer and solid tumors

Breast Cancer (Locally Advanced or Metastatic)Advanced Solid CancersMetastatic (Stage IV) Breast CancerOvarian CancerEndometrial Cancer

Part of Cancer, Hormones & metabolism, Skin, Women’s health & pregnancy clinical trials.

This study tests a new drug called INV-6452 to see if it is safe and can help control advanced cancers that have grown despite prior treatment. The drug targets specific cancer cell weaknesses, particularly in hormone-sensitive breast cancers without HER2 mutations.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
201 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Age 18 or older
  • Advanced or metastatic cancer (spread beyond original site) confirmed by biopsy, with measurable tumors
  • Cancer progressed after standard treatment, or you cannot tolerate standard options
  • Good overall health and life expectancy greater than 3 months (ECOG score 0–1)
  • Normal blood counts, liver, and kidney function
  • Willing to provide tumor tissue sample or accept a pre-treatment biopsy

View the official record on ClinicalTrials.gov

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Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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