Clin2
NCT07618858Possibly a fitNot yet recruiting

Comparing citrate and heparin to prevent clotting during dialysis

End-Stage Kidney DiseaseHemodiafiltrationChronic HemodialysisRenal Failure

Treatments studied

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This study compares two ways to prevent blood from clotting during a type of dialysis called hemodiafiltration. You may get either a standard drug (heparin) or a newer approach using citrate to keep your dialysis filter from clotting.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years of age or older.
  • You have end-stage kidney disease and are on regular hemodialysis three times a week.
  • You have a working arteriovenous (AV) fistula, which is a connection between an artery and vein used for dialysis.
  • You are not currently taking blood thinners (anticoagulants) or two antiplatelet drugs together (like aspirin and clopidogrel).
  • You do not have a bleeding disorder, active bleeding, or acute kidney injury.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07679568Not yet recruiting
Comparing two blood thinners during continuous dialysis

This study compares two blood-thinning medications used during continuous dialysis for acute kidney injury: one uses citrate (a chemical that prevents clotting) and the other uses heparin (a standard blood thinner). By looking at how well these treatments work, the study aims to find the safest and most effective way to keep the dialysis filter working.

Munich, Bavaria
NCT07518303Not yet recruiting· Phase 4
Comparing two blood thinners for kidney dialysis in sepsis

This study compares two ways to prevent blood clots during kidney dialysis in people with sepsis-related kidney failure. The goal is to see which method is safer and works better to keep the dialysis filter working properly.

NCT06021080Recruiting
Comparing kidney dialysis patterns on calcium levels with citrate blood thinner

This study compares different patterns of continuous kidney dialysis (called CRRT) to see how they affect calcium levels in the blood when using a citrate-based blood thinner. It may help find the safest way to manage calcium during treatment.

Fuzhou, Fujian
NCT06224140Recruiting
Dialysis without heparin: a safety study

This study tests whether dialysis can be done safely without using heparin (a blood thinner) in people with end-stage kidney disease. If successful, it could reduce the need for blood-thinning medications and their associated risks.

Marseille, Bouches du Rhône
NCT07751874Not yet recruiting
Dialysis with citrate for kidney failure in the ICU

This study tests a special blood-filtering treatment for patients in the intensive care unit (ICU) with acute kidney injury. It uses a medicine called citrate to prevent blood clotting during dialysis, which may be safer for patients whose liver cannot process citrate normally.

Edegem, Antwerp
NCT06908746Recruiting
Citrate Anticoagulation in Dialysis for Liver and Kidney Failure

This trial looks at whether a blood thinner called citrate is safe and effective in patients who have both kidney and liver failure while on continuous dialysis in the ICU. It may help guide treatment for people with serious organ problems.

Edegem, Antwerp

Hear when a new End Stage Kidney Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.