Testing a New Cancer Drug in Healthy Chinese Men
Treatments studied
This study tests how a new drug called AK104 works in the body by measuring how it moves through the bloodstream. Researchers are looking for healthy men to help understand if this drug is safe and how it behaves, which could eventually help cancer patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy male aged 18–45 years
- Your weight is between 121–165 pounds and your BMI (body size) is between 19–26
- You have no serious medical conditions (heart, lung, kidney, diabetes, autoimmune disease, or cancer history)
- You are willing to use birth control for 6 months after the study and not donate sperm
- You can attend all study visits and have blood tests done regularly
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 1/2 trial tests a combination of two immune-targeting drugs (AK109 and AK104) in people with advanced solid tumors that can’t be treated with standard options, or where standard treatment didn’t work or wasn’t tolerated. It aims to find safe dosing and whether the treatment can shrink tumors or control the disease.
This Phase 1 study tests the safety and early anti-cancer activity of AK127 given together with AK104 in people with advanced solid tumors. You may be considered if standard treatments have already been tried or aren’t suitable for you.
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This trial is testing an experimental drug called LY4066708 in healthy people to see how safe it is and how the body processes it. It may help researchers understand if the drug can be used in future studies for conditions like Alzheimer's disease.
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