Laroprovstat and rosuvastatin vs. rosuvastatin for high cholesterol
Part of Hormones & metabolism clinical trials.
This trial tests whether adding a new medicine, laroprovstat, to a standard cholesterol drug (rosuvastatin) is better at lowering bad cholesterol than the standard drug alone. It might help people who are at high risk for heart disease or stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years of age or older
- Be taking a stable dose of cholesterol-lowering medicines
- Be on the highest dose of a statin you can tolerate
- Have had a heart-related event (like a heart attack or stroke) or be at high risk for a first event
- Not be of Asian origin (trial excludes Asian participants)
- Not have uncontrolled high blood pressure, uncontrolled type 2 diabetes, or poorly treated underactive thyroid
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new combination pill containing two cholesterol-lowering medications (laroprovstat and rosuvastatin) in people who have never taken cholesterol medicine before. The goal is to see if the combination works better than either medicine alone at lowering LDL cholesterol, which is the 'bad' cholesterol that can increase heart disease risk.
This trial compares two very low LDL-cholesterol targets (below 1.0 vs 1.0-1.39 mmol/L) using extra medications (PCSK9 inhibitors) to see which is safer and better for people at extremely high risk of heart attacks or strokes.
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
This study compares a new cholesterol medication combination to a standard high-intensity statin in patients aged 75 and older who have had a heart procedure to open blocked arteries. The goal is to see which treatment is better at managing cholesterol and reducing future heart risks.
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
This study tests an experimental drug (QLC7401) that may help lower LDL ('bad') cholesterol in people who already have high cholesterol or mixed hyperlipidemia. If you're on stable cholesterol medication but still need more lowering, this trial could offer another option.
Hear when a new Hypercholesterolaemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.