Clinical trials
Hypercholesterolaemia clinical trials
Below are recruiting hypercholesterolaemia clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05621070RecruitingPhase 3
Test drug JS002 for high cholesterol not at goal
This Phase 3 study tests whether JS002 alone can lower LDL “bad” cholesterol in people whose levels are still too high for their heart-risk level. It will also check how safe the treatment is, especially for heart and metabolic side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT07206472Recruiting
Study of bempedoic acid for high cholesterol
This study observes patients with high cholesterol or mixed lipid disorders who are taking bempedoic acid, alone or with ezetimibe, to see how it works in real life. It aims to gather information that may help doctors better manage cholesterol.
Belo HorizonteAges 18 years+ - NCT02693548Recruiting
Study of families with familial high cholesterol
This is a study that follows people with a genetic form of very high cholesterol (familial hypercholesterolemia) and their close relatives. It aims to better understand this condition in real families and how it affects health over time.
MadridAges 15 years+ - NCT06974266Recruiting
Probiotic for high cholesterol in overweight adults
This trial tests a natural probiotic called Akkermansia muciniphila to see if it can help lower cholesterol in people who are overweight. It is for adults who have not been on cholesterol medication recently and are managing their levels with diet and exercise.
Zibo, ShandongAges 35–75 - NCT06884098RecruitingPhase 1
A study comparing two versions of a medicine in healthy adults
This trial tests a new version of a medicine (AD-228B) against the original (AD-2284) to see how they work in the body and if they are safe. Healthy volunteers are needed.
SeoulAges 19 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Foley, AlabamaAges 18–75 - NCT07491172RecruitingPhase 1
Trial of CTX310 for stubborn high cholesterol and fats
This trial tests a new medicine, CTX310, for people with persistently high levels of fats (triglycerides) and cholesterol that have not improved with standard treatments. It aims to see if the drug is safe and tolerable.
Hialeah, FloridaAges 18–75 - NCT04272697Recruiting
Registry study for familial cholesterol conditions
This trial is a global registry that collects health and genetic information from people with familial hypercholesterolemia (FH) and sometimes from their relatives. The goal is to better understand FH and how it presents, which can help improve care for families affected by high cholesterol.
LondonAges Any age - NCT06501443RecruitingPhase 4
Study of inclisiran after heart attack or stroke
This study tests a cholesterol-lowering injection (inclisiran) given soon after a heart attack, urgent heart procedure, or stroke. The goal is to see if it helps lower bad cholesterol quickly and safely.
CorrientesAges 18–100 - NCT06743659Recruiting
Decision support tool for familial high cholesterol
This trial tests a computer tool that helps doctors identify and manage people with familial high cholesterol. It aims to improve care for those who may not yet have a diagnosis.
Boston, MassachusettsAges Any age - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07375225Recruiting
Alirocumab 300mg adherence study in Italy
This study tracks how well patients stick to and benefit from alirocumab 300mg, a cholesterol-lowering injection. It looks at real-world use in Italy.
Naples, NapoliAges 18–80 - NCT07614958RecruitingPhase 3
Testing a new cholesterol medicine against bempedoic acid
This study compares two new medicines—obicetrapib and bempedoic acid—to see which one better lowers cholesterol in people whose cholesterol remains high despite taking standard medications. If your cholesterol isn't controlled well enough with current drugs, this trial may help you access an experimental treatment.
Stockton-on-TeesAges 18 years+ - NCT06646354Enrolling by invitationPhase 3
Study of two experimental drugs for high blood pressure and cholesterol
This trial tests whether taking two experimental drugs together can safely lower both high blood pressure and high cholesterol. It may be an option if you have both conditions and your blood pressure is not extremely high.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for hypercholesterolaemia?
- Yes. Clin2 currently lists 14 recruiting hypercholesterolaemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypercholesterolaemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypercholesterolaemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.