Laser Heat Therapy Plus Immunotherapy for Recurrent Brain Tumors
Treatments studied
Part of Cancer clinical trials.
This trial tests a minimally invasive laser procedure combined with a new immunotherapy drug (cemiplimab) to treat glioblastoma that has returned after initial treatment. The laser heats and destroys the tumor while the immunotherapy helps your immune system fight remaining cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Confirmed glioblastoma (grade 4 brain tumor) that has come back after standard treatment
- At least 12 weeks since completing initial surgery, radiation, and chemotherapy (temozolomide)
- Your tumor must be in a location and size suitable for laser treatment, as determined by your neurosurgeon
- At least 18 years old with adequate blood counts and organ function (liver, kidney, blood clotting)
- Good enough overall health and function to tolerate the procedure and study drugs (Karnofsky score ≥60%)
- Willing to use effective birth control for 4 months after the study (or longer depending on which treatment arm)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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