Clin2
NCT07623460Possibly a fitNot yet recruiting

Zanzalintinib after Pluvicto for prostate cancer

mCRPC (Metastatic Castration-resistant Prostate Cancer)

Treatments studied

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new oral drug, zanzalintinib, for men with advanced prostate cancer that has stopped responding to hormone therapy and who have already been treated with Pluvicto. The goal is to see if this drug can slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have metastatic castration-resistant prostate cancer (cancer that has spread and no longer responds to hormone therapy).
  • You have already received at least one dose of Pluvicto (a targeted radiation therapy).
  • You have not had chemotherapy for your metastatic prostate cancer (but you may have had it earlier).
  • Your kidneys, liver, and blood counts are within acceptable ranges.
  • You have not had other cancers recently (except for simple skin cancers).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07608718Not yet recruiting· Phase 2
Zanzalitinib for advanced prostate cancer that has stopped responding to hormone therapy

This study tests a new oral medication called zanzalitinib, which may help slow the growth of advanced prostate cancer that has continued to spread despite hormone therapy and possibly chemotherapy. The goal is to see if the drug is safe and effective for men with this type of cancer.

Cleveland, Ohio
NCT07218666Recruiting· Phase 2
Zanzalintinib for aggressive prostate cancer

This trial tests a new drug, zanzalintinib, in men with a fast-growing type of prostate cancer that has spread and stopped responding to standard hormone therapies. It aims to see if the drug can help shrink tumors or slow the disease.

Milwaukee, Wisconsin
NCT07185945Not yet recruiting· Phase 2
Zanzalintinib for advanced bladder cancer after previous treatment

This trial tests a new drug called zanzalintinib for people with advanced bladder cancer that has grown after at least one prior treatment. The drug may help shrink tumors or slow their growth.

NCT07042919Recruiting· Phase 1/Phase 2
Zanzalintinib for advanced liver cancer after prior treatment

This trial tests a new drug called zanzalintinib for people with advanced liver cancer (HCC) that can't be treated with surgery. You may join if your cancer has gotten worse after at least one prior treatment, or you couldn't tolerate that treatment.

Chicago, Illinois
NCT07750158Recruiting· Phase 3
Zanzalintinib for colorectal cancer with residual tumor dna

This trial is testing a new drug (zanzalintinib) alone or with pembrolizumab to see if it can stop cancer from coming back in people with colorectal cancer who have no visible cancer on scans but still have tumor DNA in their blood.

Council Bluffs, Iowa
NCT07714551Not yet recruiting· Phase 2
Zanzalintinib for advanced pheochromocytoma and paraganglioma

This trial tests a new oral medication called zanzalintinib for adults with a rare type of tumor called pheochromocytoma or paraganglioma that has spread or cannot be removed with surgery. The goal is to see if this drug can slow or stop the tumor from growing, and to evaluate its safety.

Boston, Massachusetts

Hear when a new mCRPC (Metastatic Castration-resistant Prostate Cancer) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.