Clin2
NCT07624305Possibly a fitRecruiting

Balcinrenone and Dapagliflozin for Moderate-to-Severe Kidney Disease

Renal Insufficiency, Chronic

Treatments studied

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests a combination of two medications (balcinrenone and dapagliflozin) to help protect your kidneys if you have moderate-to-severe chronic kidney disease. The trial evaluates whether this combination slows kidney damage and improves kidney health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
2,800 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • Age 18 or older
  • Diagnosed chronic kidney disease with specific kidney function and protein levels
  • Normal to low potassium levels (≤5.0 mmol/L)
  • Currently on maximum tolerated ACE inhibitor or ARB for at least 4 weeks
  • Not requiring dialysis or expected to need it within 3 months
  • No recent heart attack, stroke, or major heart surgery in the past 3 months

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06307652Recruiting· Phase 3
Testing a new heart failure and kidney treatment combo

This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.

Alexander City, Alabama
NCT07754331Recruiting· Phase 1
Effect of hemodialysis on balcinrenone and dapagliflozin

This study is testing two investigational drugs, balcinrenone and dapagliflozin, in people with kidney failure who are on hemodialysis. The purpose is to see how your body processes these drugs when you are on dialysis, and to make sure they are safe.

Orlando, Florida
NCT06742723Recruiting· Phase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure

This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.

Fairhope, Alabama
NCT07239570Recruiting· Phase 4
Using biomarkers to personalize kidney disease treatment

This study tests if matching treatments to your specific kidney disease markers can better protect your kidneys. It looks at how well Finerenone, Dapagliflozin, and Semaglutide work alone or in a sequence.

Herlev
NCT06398977Recruiting
Dapagliflozin to protect kidney function in dialysis patients

This trial tests whether a diabetes drug called dapagliflozin can help people on peritoneal dialysis keep their remaining kidney function longer. It is for patients who started dialysis recently and still make urine.

Chengdu, Sichuan
NCT07598864Not yet recruiting· Phase 3
Adding finerenone to dapagliflozin for kidney protection in diabetes

This study tests whether adding a second medicine (finerenone) to a common diabetes/kidney medicine (dapagliflozin) helps reduce protein in the urine and protect the kidneys better than using dapagliflozin alone.

Chittagong

Hear when a new Renal Insufficiency, Chronic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.