Clin2
NCT07625384Possibly a fitNot yet recruiting

Testing Two Drugs for Adult-Onset Still's Disease

Still Disease

Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.

This study tests whether two injectable medicines (goflikicept and olokizumab) work safely as a second treatment for adults with Still's disease, a rare inflammatory condition. If you've already tried one treatment without enough improvement, this trial may help.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
52 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a confirmed diagnosis of Adult-Onset Still's Disease (AOSD)
  • Your disease is active or has low disease activity right now
  • If you take corticosteroids, your dose must be stable for 2+ weeks (max 60 mg/day prednisolone equivalent)
  • If you take methotrexate, your dose must be stable for 4+ weeks (max 30 mg/week)
  • You can visit the clinic regularly, receive injections, and follow study instructions
  • You agree to use effective birth control for at least 8 weeks after your last study injection

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07126145Not yet recruiting
Autoinflammatory Disease Long-term Study

This study will follow people with adult-onset Still's disease or similar autoinflammatory conditions to learn more about these illnesses over time. By participating, you can help doctors better understand and treat these conditions.

NCT05927454Recruiting
RaDiCo Acostill study for inflammatory fevers and arthritis

This is a long-term study that collects health information and lab samples from people who have certain diagnoses of recurring (coming and going) inflammatory fevers and related joint or immune conditions. It may help researchers better understand these diseases and how they work over time.

Paris, Île-de-France Region
NCT07191444Recruiting
Study comparing firsekibart to anakinra for adult-onset Still's disease

This trial tests a new drug called firsekibart against an existing drug, anakinra, for people with active adult-onset Still's disease. It aims to see if firsekibart is more effective in controlling symptoms like fever, joint pain, and rash.

Shanghai, Shanghai Municipality
NCT07203001Recruiting· Phase 2
MAS825 for Still's disease in children and adults

This trial tests a new drug called MAS825 for people with Still's disease that is still active despite other treatments. It aims to see if the drug can reduce symptoms like fever, rash, joint pain, or a serious complication called macrophage activation syndrome.

Cincinnati, Ohio
NCT07175285Recruiting
Study for lupus patients not helped by steroids and 2 immunosuppressants

This trial tests a new treatment for people with active lupus who haven't responded well to steroids and at least two other immune-suppressing drugs, including a biologic. It aims to find a better option for controlling lupus symptoms.

Mesa, Arizona
NCT03510442Recruiting
Study of joint illness patterns and genes in juvenile and adult diseases

This study follows people with systemic juvenile idiopathic arthritis (sJIA), adult-onset Still’s disease (AOSD), and similar conditions to learn how the illness works over time. It also collects blood and family information to study genetics and explain what causes flare-ups, which may help future care.

Bethesda, Maryland

Hear when a new Still Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.