New Blood-Cell Growth Drug After Bone Marrow Transplant
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new medication called luspatercept to help patients whose red blood cells aren't recovering well after a bone marrow transplant for blood cancer. The goal is to see if it works better than the standard treatment (epoetin) to boost red blood cell production.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have a blood cancer (like leukemia, lymphoma, or myeloma) that went into remission after your bone marrow transplant
- Your red blood cells are not recovering properly after your transplant, despite time passing
- You have not previously taken epoetin (a standard red blood cell growth medicine)
- Your natural erythropoietin level (a hormone that stimulates red blood cell growth) is low
- Your overall health is stable enough to tolerate the trial (your doctor rates you as able to do light activities or better)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a drug called luspatercept can help your body produce red blood cells better after a bone marrow transplant for blood cancer. The goal is to reduce complications and improve recovery.
This study tests a drug called luspatercept to see if it can help people who have low red blood cells (anemia) after a stem cell transplant for leukemia. It may improve your energy and reduce the need for blood transfusions.
This trial tests if luspatercept can help improve red blood cell counts in people with a certain type of acute myeloid leukemia (AML) who have mild to moderate anemia after intensive chemotherapy. It is for patients with a lower-risk form of AML who have completed 1–3 cycles of high-dose consolidation therapy.
This trial tests whether luspatercept can help improve low red blood cell counts (anemia) that happens soon after a stem cell transplant. It is for people with blood cancers who have very low hemoglobin after transplant.
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This Phase 2 trial studies whether luspatercept can improve anemia in people with lower-risk myelodysplastic syndrome (MDS) who do not currently need red-blood-cell transfusions. It’s also looking to see if the benefit is similar whether or not you have ring sideroblasts.
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