Study of vision changes in limbal stem cell deficiency
Part of Eyes & vision clinical trials.
This observational study follows patients with limbal stem cell deficiency (a condition affecting cells at the edge of the cornea that help maintain healthy eye surface) to understand how their vision changes over time. Researchers will track your eye health without giving you new treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of limbal stem cell deficiency in at least one eye before enrollment
- Your vision (best corrected) in the study eye is 70 letters or worse on an eye chart at two visits
- Your vision did not change by more than 10 letters between your screening visit and day 1
- You do not have any active eye infection in either eye
- You do not have active inflammation inside the eye (iritis or uveitis) in either eye
- Eye doctors confirm your retina is healthy enough that you could potentially see better
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new eye drop called CSB-001 for people with limbal stem cell deficiency (LSCD), a condition that damages the cornea. The goal is to see if the drops can help improve the health of the cornea and reduce inflammation.
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
This trial studies a type of eye surface transplant to help when the eye’s limbal “stem cells” are missing or not working well. If you have severe limbal stem cell deficiency in one or both eyes, this treatment may help the eye heal and stay healthier.
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This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
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