Eye surface repair for limbal stem cell deficiency
Part of Eyes & vision clinical trials.
This trial tests a treatment that uses your own eye cells to repair the surface of the eye. It may help if you have severe damage to the clear front layer of your eye.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe or complete loss of the eye's surface cells (called limbal stem cell deficiency) in one or both eyes.
- The condition can be caused by any reason, such as injury, infection, or other eye diseases.
- You are willing to undergo a procedure to collect and grow your own cells for transplantation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
This study tests a new eye drop called CSB-001 for people with limbal stem cell deficiency (LSCD), a condition that damages the cornea. The goal is to see if the drops can help improve the health of the cornea and reduce inflammation.
This trial tests a new way to repair the eye surface by using a thin sheet of cells from your own mouth, which are grown in the lab and then placed on your eye. It may help people whose eye damage hasn't improved with other treatments and who have very poor vision.
This observational study follows patients with limbal stem cell deficiency (a condition affecting cells at the edge of the cornea that help maintain healthy eye surface) to understand how their vision changes over time. Researchers will track your eye health without giving you new treatment.
This Phase 1/2 trial tests a treatment made from your own mouth tissue cells to help regrow the front surface of the eye when both eyes have severe limbal stem cell deficiency. If you qualify, you may receive an autologous (made from your own tissue) cell sheet to improve eye healing and vision.
This trial tests an eye drop called BRM421 for people with mild to moderate limbal stem cell deficiency, a condition where the eye's surface doesn't heal properly. The goal is to see if this eye drop helps improve the eye's surface and reduce symptoms.
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