Fat-derived cells injection for hard-to-treat reflux disease
Part of Digestive system clinical trials.
This trial tests injecting special cells from your own fat tissue into your esophagus to help reduce severe acid reflux that hasn't improved with standard medications. The goal is to strengthen the valve that prevents acid from backing up.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–75 years
- Moderate-to-severe acid reflux confirmed by testing, either not controlled by acid-blocking drugs or requiring high doses to work
- Normal or near-normal esophagus muscle function (ruled out by specialized swallowing test)
- Willing to have a small fat sample harvested from your body and receive the cell injection
- No large hiatal hernia (opening in diaphragm), severe ulcers, Barrett's esophagus with abnormal cells, or achalasia (severe swallowing difficulty)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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