Aprepitant to Help You Go Home the Same Day After Knee Surgery
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This study tests whether a medication called aprepitant can help prevent nausea after total knee replacement (TKA) surgery, so you can safely go home the same day instead of staying overnight. Nausea is common after surgery and can delay discharge.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having your first total knee replacement surgery (not a revision or repeat surgery)
- Your surgery is planned and not an emergency
- You will receive regional anesthesia (numbing medication around your spine), not general anesthesia that puts you to sleep
- You are between 18 and 90 years old
- You speak English or Spanish
- Your liver function is normal or only mildly abnormal
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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