Clin2
NCT06357234Possibly a fitRecruiting

Aprepitant to prevent nausea after child scoliosis surgery

Spinal FusionNausea and Vomiting, PostoperativeAnesthesia

Treatments studied

Part of Bones, joints & muscles clinical trials.

This trial tests if a drug called Aprepitant, given before surgery, can better prevent nausea and vomiting after scoliosis repair in children. It is for children aged 8 to 18 who are having spinal fusion surgery for a certain type of scoliosis.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
8 years to 19 years
Study type
Interventional

Who can take part

  • Your child must be having spinal fusion surgery for scoliosis where at least 6 bones in the spine are fused together.
  • The scoliosis must be of the 'idiopathic' type, meaning the cause is unknown, not due to another condition.
  • Your child must be between 8 and 18 years old on the day of surgery.
  • Your child must weigh more than 40 kg (about 88 pounds).
  • Your child cannot have a known allergy to the study drug, Aprepitant, or be taking certain medications that interact with it.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06067893Enrolling by invitation· Phase 4
Low dose sedation medicine for pain after scoliosis surgery

This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.

Kansas City, Missouri
NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines

This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.

Boston, Massachusetts
NCT06543966Not yet recruiting· Phase 3
Aprepitant shot for preventing nausea after gynecologic or abdominal surgery

This trial tests an aprepitant injection to prevent nausea and vomiting after laparoscopic gynecologic or abdominal surgery lasting at least 1 hour. It may be an option for people who want to reduce post-operative sickness.

NCT07371728Not yet recruiting· Phase 4
Testing aprepitant for nausea after ear surgery

This study tests whether a medication called aprepitant can reduce nausea and vomiting after middle ear surgery. If you are having certain types of ear surgery under general anesthesia, you may be able to join.

Montreal, Quebec
NCT06887621Recruiting· Phase 2
Adding oral amisulpride to prevent nausea after gynecologic surgery

This trial tests if adding a medication called amisulpride to standard anti-nausea drugs can better prevent vomiting and nausea after gynecologic surgery. It is for women at high risk of postoperative nausea.

São Paulo, São Paulo
NCT04153994Recruiting
Numbing injection study for kids’ scoliosis back surgery pain

This trial tests whether a specific numbing injection (placed in the muscles of the back) can improve pain control for children having one-stage scoliosis surgery. It may help reduce post-surgery pain needs and improve comfort.

Palo Alto, California

Hear when a new Spinal Fusion trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.